What he/she says
Treatment received for my wife for Castleman’s Disease
In April-2017, My wife’s felt an enlarged lymph node under her arms. We consulted my wife’s gynecologist who did an ultrasound and confirmed it is a mild case of infection leading to enlarged lymph nodes and she prescribed antibiotics for a week. But the size of lymph node did not return to normal. We then went to another hospital for consultation, where the doctor advised to do a FNAC test. The FNAC test results also confirmed that the enlarged lymph nodes were due to reactive adenitis (may be infection). She was then prescribed another set of high dose antibiotics for nearly 2 weeks, even after which the size of the lymph node did not return to normal.
In June-2017, my wife had severe stomach pain resulting in admission to citizens hospital under Dr. Sarada (Gastroenterologist). She then ran a series of tests to find out a reason for my wife’s stomach pain, but nothing came up positive.
Dr. Sarada then advised an open-biopsy for the enlarged lymph node to rule out any other reason for stomach pain. The pathological results of the lymph node showed that this is a case of Castleman’s disease (hyaline vascular type). We came to utter shock about the diagnosis and were worried as the doctors informed that this is a very rare disease and has very limited treatment options available in India. We were then referred to Dr. SK Gupta who is a pure hematologist practice only for liquid organs (blood, bone marrow, spleen, & lymph nodes) disorders for consultation. My wife now started to have fever for every 8 hours which was not subsiding, and no one was able to confirm whether the disease if causing these symptoms.
Dr. SK Gupta then ordered a few series of tests to rule out any other possibilities of this disease. The final diagnosis was confirmed that multicentric Castleman’s disease (Hyaline vascular form). Gupta sir then reassured that this can be treated without much side effects of the drugs. He was also very open and informed us a get an 2nd opinion, if we feel to go for it. We did get 2nd opinion from another hospital where they also agreed with Dr SK Gupta sir treatment.
We then decided to continue with Dr. SK Gupta and AOI for treatment. My wife received treatment with 6 cycles of rituximab weekly for 6 weeks and then oral steroids for 6 weeks. Gupta sir was very patient in answering all our queries during the treatment cycle. Just after 2 cycles my wife’s symptoms started to resolve. By the end of 6th cycle of rituximab my wife completely became normal. Gupta sir then asked us to continue steroids for another few weeks after which he tapered the dose of steroids gradually. By Nov-2017, my wife’s treatment was complete, and all her blood work up became normal and her lymph nodes reduced in size.
We are currently following up every 3 months with blood tests and every 6 months with ultrasound scans. The size of lymph nodes is currently stable and my wife symptoms are completely gone. We last followed on 1st March 2019 and with help of god blessings plus Dr SK Gupta sir guidance, exceptionally well care things are fine. My wife rejoined her job soon after treatment and now its almost 18months since treatment completed and we r thinking to have 2nd baby to compete our family.
- Date 11 Jun 2016
- Doctor Name Dr. SK GUPTA
- Category Liquid Organ Cancer Disorders, Liquid Organ Non-Cancer Disorders