Haploidentical bone marrow transplant

What is Haploidentical bone marrow transplant?

A haploidentical bone marrow transplant is performed when the donor exactly matches half of the recipient’s DNA. Haploidentical bone marrow transplant is a type of allogeneic transplant. In an allogeneic transplant, the cells from donors are transplanted in the recipient to suppress the disease-causing cells or elements and restore the immune system of the patient. The key to a successful allogeneic transplant is finding the right donor. In most cases, the donors are the blood relatives of the patient. The match is proved through tissue typing. Human Leukocyte Antigens (HLA)  are the proteins that are used for tissue typing. These proteins are present in white blood cells and tissues. HLA is present almost all over the body. Donors closely matching your HLA or umbilical cord blood can be transplanted. Healthy, blood-forming cells from a half-matched donor are transplanted to replace the unhealthy ones of the recipient. This is a Haploidentical bone marrow transplant. The donor is typically a family member in Haploidentical bone marrow transplant.  The donor matches exactly half of the HLA of the donor. 

Who can be a haploidentical donor?

The patient’s mother, father, or offspring are half-matched or haploidentical donors. Siblings have a 50% chance of being haploidentical for each other. Parents are always haploidentical to their children. It is highly unlikely for uncles, aunts, and cousins to be half-match of the patient. 

Benefits of a haploidentical bone marrow transplant

For patients suffering from rare disorders, haploidentical stem cell transplants are a blessing. It is a boon especially for patients suffering from blood disorders that do not have any cure yet. Since this medical procedure does not need a complete HLA match of the donor’s tissue, it is a treatment option for 70% of the patients suffering from rare and complex disorders. Haploidentical bone marrow transplant gives a chance to live for the patients who do not have an HLA-identical sibling donor. 

A half-match donor saves a lot of hassle for the family and doctors. It avoids the need to find an alternative donor who is unrelated to the patient. It also expands the donor pool who are not a complete match for the receiver. 

In a bone marrow transplant, the patient’s immune system is wiped out so that the immune system does not reject the donated marrow. It is done to avoid the host -versus- graft effect as the response of the donor immune system can harm the new immune system during the marrow transplant. In haploidentical bone marrow transplant, the bone marrow suppresses the immune system instead of wiping it out. It is viable to perform this procedure on children with benign hematologic disorders if no donors are available with engraftment rates of 70%, durable graft in 67%. The overall survival of haploidentical bone marrow transplant is 60%.

It is generally assumed that the side-effects of a haploidentical transplant are higher than a full-matched transplant if the procedure is performed in a busy institute. In Hematology and BMT Institute International every procedure is performed with precision and patients are given utmost care. Dr. S.K Gupta, the founder of Hematology and BMT Institute International has 15 years of experience and is an expert in Haploidentical bone marrow transplant. He started his medical career as a nursing student and has been trained at various reputed & prestigious healthcare Institutions in India.

If you are looking for a medical institute that provides quality healthcare with utmost dedication and care, head to Hematology and BMT Institute International in Hyderabad. It is one of the most advanced and efficient healthcare centers in India. 




Desmond Tutu once said, “Hope is being able to see that there is light despite all of the darkness.” It all started in December 2019, when Komal’s (name changed) mother, Aruna (name changed) fell sick after attending a marriage in their village.
After medical consultation, small reddish
spots were observed on her skin, which initially appeared to be normal mosquito bites. After a couple of days, Komal took her mother, Aruna to a clinic for her regular diabetic checkup, where she also mentioned the red spots to the doctor. The doctor suggested taking a CBP test (Complete Blood Count), which showed low platelets count. The doctor advised an immediate admission to the hospital as the platelet count was below 1 lakh, and other tests revealed that she was also dengue positive. 

Aruna’s treatment went on for 10 days with no sign of improvement. Despite the proper medication, her platelet count went down to 30,000. When the family discussed with the doctor, he advised consulting a specialized Hematologist in a corporate hospital in Hyderabad. 

Upon meeting the Hematologist at the hospital, the doctor advised going for a Complete Hemogram Count(CBC) and ANA by IF test, an Antinuclear antibody test by Immunofluorescence method. By the time the family received the report,  the platelet count went down to  10,000, and ANA by IF test results were negative. The Doctor informed them that it’s not dengue, but a disease called ITP (Immune Thrombocytopenia), in which platelets get destroyed by one’s own body cells. Aruna was admitted due to the low platelet count and immediately one SDP (Single Donor Platelets) was transmitted. Her platelet count rose above 1 lakh and she was discharged the next day but the doctor advised her to stay on medication, and she was kept under steroids (Omni Cortile & Romiplostim) for a month. Despite the regular medication, Aruna’s health was not improving,  platelets were about 20,000 on and off, so 6 packets of SDP were transmitted again. As there was no development in her condition, the doctor advised further tests; a Bone Marrow Biopsy to check the functionality of the bone marrow.

Only after the tests did the family found out that Aruna was suffering from Severe Aplastic Anemia. In such conditions, the bone marrow does not make enough blood cells for the body to function smoothly. 

A doctor suggested taking an appointment with Dr.S.K.Gupta in Hematology BMT Institute International. He is one of the best hematologists in India and a specialist in treating blood disorders, bone marrow, lymph nodes, and spleen disorders.
Dr.S.K.Gupta studied the reports and explained that the patient did not suffer from ITP, but confirmed that she had Severe Aplastic Anemia. The doctor patiently elucidated the entire situation to the family, which helped them to get a better understanding of the disorder. 

On 16th Feb 2020, the patient was admitted to Hematology BMT Institute International under the supervision of Dr. S.K.Gupta. On the first day, CBP test reports showed that the platelets were very low,  so the doctor advised to have an SDP transfusion and other initial baseline procedure tests like CT, MRI, abdominal ultrasound test. Aruna was discharged for a few days until the final reports were examined by Dr. Gupta.

Aruna was admitted to the hospital after a week and the treatment procedure was immediately taken over by Dr. Gupta and his team. Dr.S.K. Gupta visited her every day to check her health. Along with the treatment, Dr.Gupta also arranged counseling sessions every week to clear doubts regarding the treatment. 

During Aruna’s treatment for the last 6 months, she received only a single RDP (Random Donor Platelets) and RBC (Red Blood Cells) through transfusion. 

Dr.S.K.Gupta was also very patient in answering the questions and did not hesitate to respond to doubts and queries of the patient and family. Komal commented, “I strongly recommend Dr.S.K.Gupta not because he treated my mother but, because his knowledge and passion towards treating his patients are impeccable.” 

Dr.S.K.Gupta is one of the best hemato-oncologist doctors in Hyderabad. With over 15 years of experience, he’s an expert in treating blood disorders like Leukemia, Lymphoma, Multiple Myeloma, Aplastic Anemia, Thalassemia and Sickle Cell disease, Hemophagocytic syndromes, Immunodeficiencies, and spleen disorders. Dr.Gupta says that proper monitoring of the patient’s condition and boosting the morale of both the patient and the family are the key steps in reducing morbidity and mortality during the treatment. 

The Hematology and BMT Institute International in Hyderabad is the best in treating any blood-related disorders.
If you want to book an appointment or want to connect with Dr.Gupta, then visit
https://hematologybmt.com/ or contact at 7780297660. 



A diagnosis of blood cancer can change lives; not only for the patients but also for their family and friends who love them. Let’s look at Bhavya’s (name changed) cancer treatment journey and experience with Dr. S.K. Gupta at Hematology BMT Institute International

Bhavya was 6 years old when she was diagnosed with blood cancer. It all started in mid-January 2019 when she started suffering from fever, cough, and cold. She also started losing weight drastically. Her family took her to a local hospital at Shadnagar but no difference was seen in her health. As time passed by, the fever started rising along with tremendous weight loss and mouth ulcers. The Government Hospital at Shadnagar conducted various tests and asked her family to take her to any good hospital. Later, Bhavya’s family took her to their native place located in Solapur, Maharashtra.

In March 2019, she was admitted to Markandeya Sahakari Rugnalaya under the observation of Dr. Shrishi Keyur. Treatments started and several tests were performed. The doctor after studying the results told Bhavya’s uncle that Bhavya is diagnosed with cancer. Her family tried consulting various other doctors but none of them matched their expectations. Finally, Bhavya’s uncle, Anand (name changed) insisted on consulting a Paediatric Hematologist, Dr. Dhinanth Mangeshkar in Pune.  The doctor informed the family that Bhavya is suffering from blood cancer and it has already spread across 95% of her body. The doctor insisted on starting the treatment immediately.

Amidst the dilemma, Bhavya’s family came to know about Dr. S.K. Gupta, senior consultant and founder at Hematology BMT Institute International, Hyderabad. Upon reaching the hospital, Prema, Dr. Gupta’s assistant, received them and took a brief medical history of Bhavya. Dr. Gupta guided Bhavya and her family through blood cancer and its treatments. Her family felt relaxed after receiving the doctor’s counseling. Bone marrow, Fisher mark, and other tests were done to understand what exactly is the case. Dr. Gupta then started Chemotherapy, which was a difficult phase for Bhavya and her family. Bhavya’s Chemotherapy lasted for 4 months. It was a difficult phase especially when the WBCs and platelet count were being closely monitored. During these times, the hospital management was so keen and supportive that it made it easier for the family to stay strong. Dr. Gupta spent time listening and answering the patient and her family member’s questions. He treated Bhavya as his child and played with her during his visits, which motivated her for a faster recovery. 

Bhavya’s mother said, “A heartfelt thanks to Dr. Gupta for my daughter’s second birth. Thanks to the management and staff for their all-time support. It was a great experience at Hematology and BMT Institute International.”

Dr. S.K. Gupta is a renowned hematologist in India with experience of over 15 years, practicing as a senior hematology consultant at Hematology BMT Institute International. He is an expert in treating blood, bone marrow, lymph nodes, and spleen disorders. Dr. S.K. Gupta strongly believes that the cornerstones of fruitful outcomes even in life-threatening hematological disorders are early diagnosis, proper guidance, and support. Adequate monitoring of the patient’s condition, improving the morale of both the patient and the family, are also crucial steps in reducing morbidity and mortality during treatment. 

At Hematology BMT Institute International, we have the best cancer doctors, who specialize in treating blood cancer with surgery, chemotherapy, bone marrow transplant, biological therapy, and hemato-oncology.


Book an appointment with Dr. S.K. Gupta, an experienced cancer specialist at Hematology BMT Institute International, one of the best cancer hospitals in India. Visit our website https://hematologybmt.com/ or call us at +91 7780297660. 


Multiple myeloma treatment in Hyderabad


Cancer begins when the cells start growing out of control. Cells can become cancerous in nearly every part of the body, and may spread to other areas. Let’s talk about Multiple myeloma, which is also known as Plasma cell cancer. The bone marrow finds normal plasma cells as an integral part of the immune system. The immune system consists of several types of cells, which work together to fight infections and other diseases. 

In the immune system, lymphocytes (lymph cells) are one of the major types of white blood cells, which include T cells and B cells. There are lymphocytes in many areas of the body, including lymph nodes, bone marrow, intestines, and bloodstream.

When blood cells respond to an infection, they ripen and mutate into plasma cells. Plasma cells then create antibodies that help the body kill germs.  Plasma cells are found in the bone marrow, the soft tissue inside the bones. Bone marrow is also the place of other blood cells, such as red blood cells, white blood cells, and platelets. 

In general, multiple myeloma is the condition when the plasma cells become cancerous and grow out of control. The plasma cells make an unusual protein (antibody) known by various names such as monoclonal immunoglobulin, monoclonal protein (M-protein), M-spike, or paraprotein. A person who has myeloma will find paraprotein often in the blood and urine. Tests of blood and urine are the means to diagnose and monitor myeloma. 

Multiple Myeloma does not constitute a lump or a tumor, however, most of the problems that it causes are due to a build-up of abnormal plasma cells in the bone marrow and body paraprotein. Myeloma affects those areas where your bone marrow is active. This includes your arms, legs, shoulders and spine, skull, pelvis, and rib cage. Myeloma affects several places in the body which is why it is referred to as multiple myeloma.

Blood and Myeloma

To understand why myeloma affects one’s body, it is important to know what and how blood cells are produced. Usually, when a body needs blood, the bone marrow makes blood cells in a controlled way. All the blood cells originate from the same cell type, called a stem cell. As they develop (mature), they transform into one of the three blood cell types: RBCs, WBCs, and Platelets.

Plasma cells develop from a type of white lymphocytes called B blood cells. Too many plasma cells are made in myeloma, and all are of the same kind. They clutch onto the bone marrow, which means there is insufficient space to make normal white cells, red cells, and platelets. The symptoms of multiple myeloma include bone problems, low blood counts, hypercalcemia, spinal cord compressions, nerve damage, hyperviscosity, kidney problems, and infections. 

To know more about the treatment of Multiple Myeloma and its symptoms, please consult Dr. S. K Gupta.
Dr. S. K Gupta is one of the best hemato-oncologists based in Hyderabad. He is an expert in treating disorders like blood, bone marrow, lymph nodes, and
spleen disordersHe started his medical career as a nursing student and has been trained at various reputed & prestigious healthcare Institutions in India. If you are looking for myeloma cancer treatment in Hyderabad, then head to Hematology and BMT Institute International. Hematology and BMT Institute International is a healthcare group that provides quality medical care to people every year. One of the most advanced healthcare centers in India, Hematology and BMT Institute International offers a comprehensive range of diagnostic and therapeutic technologies to facilitate efficient and accurate treatment.




Realizing you have cancer is not a good experience but that moment when you know you won over cancer is truly a memorable one. You might feel depressed, frightened, or even exhausted following your cancer diagnosis. Blood cancer is one such type of cancer that occurs when abnormal blood cells start growing out of control, interrupting the functioning of normal blood cells. But, with the advancement of medical science in our country, untreatable cancer diseases now have different ways of treatment. An important part of coping with any type of cancer is recognizing the feelings and emotions connected to it. Understanding what the disease is all about and what treatments can be taken will help you in fighting the disease. For a blood cancer patient and their family, it is important to understand what and when a bone marrow transplant is required and its process. 

The bone marrow creates blood stem cells which may become any form of blood cell that the body requires. Stem cells differentiate and grow continuously into different kinds of blood cells, replacing old and worn-out blood cells in the body. Billions of new blood cells are formed each day. If the stem cells are unable to generate sufficient fresh blood cells, there could be other severe health issues. These health issues can include infection, bleeding, or anemia. 

A human body requires strong stem cells to lead a healthy life. These stem cells get destroyed during cancer treatments in which case we can use Stem Cell Transplantation.

Let’s look at what Stem Cell Transplantation is:

Stem Cell Transplantation (SCT) is a process in which a recipient accepts healthy stem cells to supplement damaged stem cells. It is also referred to as bone marrow transplantation. Before SCT, the patient takes heavy doses of chemotherapy and occasionally radiation therapy to allow the body for transplantation. This is “conditioning therapy.” They move to the bone marrow after the stem cells are injected into the patient’s bloodstream to initiate the cycle of producing new, healthier blood cells, including white blood cells, red blood cells, and platelets. This cycle is called ‘engraftment’.The complete stem cell transplantation procedure differs from person to person.

Some of the general procedures involved are:

  • Evaluation and pre-transplant texting
  • Identifying the type of transplantation required for the patient.

    There are 3 types of transplantation:

    a) Autologous:-
    Involves the use of the patient’s own stem cells. After a conditioning regime, these cells are extracted, processed and restored to his or her own body.
    b) Syngeneic:- This is when the stem cells are used from an identical twin.
    c) Allogeneic:– Obtaining blood stem cells from a donor

  • Conditioning treatment: The patient receives chemotherapy or radiation to kill any of the diseased cells in the body and to establish room for the transplanted stem cells to grow in the bone marrow.
  • Transplanting the new stem cells into the patient
  • Engraftment and recovery: Transplanted stem cells continue developing and reproducing healthy blood cells. Engraftment lasts approximately two to three weeks for bone marrow or blood Stem Cell Transplantation whereas, for cord blood transplantation, the procedure requires three to five weeks. At this time, most patients remain in the hospital to be shielded from infection and treated for side effects, while selected patients might be outpatients.

Dr. S.K. Gupta is a renowned Hematologist in India, with extensive experience of over 15 years in the field of Hematology. He possesses expertise in blood, bone marrow, lymph nodes, and spleen disorders. Dr.S.K. Gupta strongly believes that early diagnosis, proper guidance & support are the cornerstones of fruitful outcomes even in life-threatening hematological disorders. 

Hematology BMT Institute International is the best hospital providing treatment for all blood-related diseases. The hospital is located in Hyderabad and is a proactive solution to the critical needs of today’s healthcare industry, mainly delivering reliable and accessible medical treatment through dedicated and qualified healthcare professionals. The aim is to introduce the highest level of knowledge and abilities used in the treatment of patients with the use of modern and innovative accessible equipment to offer great treatment at reasonable prices.

If you want to know more about blood disorders and their treatment, visit the website https://hematologybmt.com/ or contact us on +917780297660.


Bone Marrow and Bone Marrow Transplantation


Bone marrow is the thick, spongy tissue within the bones that develops red and white blood cells and platelets. As bones are present everywhere in the body so bone marrow will also be present in all parts of the body. Unspecialized Hematopoietic Stem Cells are also present in the bone marrow. These stem cells or mother cells have two properties – 

  1. Differentiation into different blood cells or daughter cells, and 
  2. Renewal into new stem cells or mother cells.

Many cancers may hinder the average production/ renewal and differentiation of such stem cells.

The bone marrow transplant is essential if the bone marrow is not healthy enough or cannot work properly due to hematological disorders or blood cancer. Bone Marrow Transplantation (BMT) is done to replace weak bone marrow with healthy bone marrow. Unlike solid organs (kidney, liver, heart) transplant, this is not a surgical process as the majority of us know/ understand. This is purely a medical procedure in which transplantation of new blood-forming hematopoietic stem cells replaces the existing weak bone marrow hematopoietic stem cells. As a result, new blood cells will be formed and will ultimately contribute to new marrow development that will cure and prevent other disorders. For bone marrow transplantation, healthy stem cells can either be extracted from the patient’s own body (autologous BMT) or from an HLA matched family or unrelated donor (allogeneic BMT). Frankly, if we speak autologous BMT is not at all a BMT as here we are using patients own hematopoietic stem cells. In autologous BMT use of the patient’s own stem cells is done to rescue him from the side effects of high-dose chemotherapy.

Dr. S.K. Gupta is a renowned Hematologist in India, practicing as a hematology consultant at Hematology and BMT Institute International with extensive experience of over 15 years in the field. He has performed over 250 Bone Marrow Transplants for patients suffering from various Hematological blood disorders in India and across the globe. He is a specialist in the treatment of all blood, bone marrow, lymph nodes, and spleen disorders. He and his team are comfortable in treating children’s also. Let’s look at some interesting points that he came across while treating one of his patients.

In 2015, a girl was diagnosed with blood cancer and had relapsed three times.  A curative therapy was used through Allogeneic Bone Marrow Transplantation as it was the mother who donated the stem cells which was only half matching  (Haploidentical )and they did not have a fully matched HLA (Human Leukocyte Antigens) donor. Due to this reason, all the other oncologists were reluctant to go on with the procedure because Allogeneic BMT/HSCT is more complicated and demanding than Autologous BMT/HSCT. This is a recent and much-needed advancement in the field of HSCT since the first successful HSCT was done 40 years ago (1968). It was even more challenging to conduct regular services due to COVID-19, especially when the hospital is treating active COVID-19 patients. Dr. S.K. Gupta not only provides excellent treatment but also patiently answers all the queries related to the illness. He motivates and urges people not to give up. 


There are few myths about BMT which need to be busted:


Patient perspective:-

  •  It is a Surgical Procedure.
  •  Surgery is the last resort in treatment, we should try some medicines and if they don’t work only then should we go with this treatment.
  • A matching blood group is a must.
  • I will receive lifelong treatment.
  • It’s a very high-risk procedure

Donor perspective:-

  • The donor will have a lot of side effects, the blood-producing capacity will go down, immunity will go down, the capacity to fight COVID19 will go down, etc.
  • Umbilical cord Hematopoietic Stem Cells are stored for the child, so there is no need to worry.

Hematology and BMT Institute International is a global healthcare hospital that provides quality care to the people. We provide guidance and treatment as per recent developments across the world. We follow strict protocols when using the equipment and while handling patients by keeping in mind the sensitive nature of the patient’s medical conditions.

Visit our website https://hematologybmt.com/ or contact us on +917780297660 to know more about hematology and the kind of treatments that Dr. Gupta provides to his patients. 






Hematologist in Hyderabad

The Basics of Hematology, Common Blood Disorders, & the Role of Hematologists

Medicine is a field that has several branches and many of which are not popular with the common man. Hematology is one of them. To understand this field, we must first begin with its origin. It is important to know whence we came, so we know where we are going.

History of Hematology

The history of Hematology dates back to 1600 BC when Egyptians found bone cancer in mummies and manuscripts. A significant advancement in blood research arrived in 1642 when Anthony Van Leeuwenhoek invented the microscope and detected blood cells. In 1770, the ‘Father of Hematology’ William Hewson created blood-clotting properties and expressed his understanding of leukocytes, or white blood cells. It was not until 1818 that James Blundell successfully performed the first documented blood transfusion between humans. Still, the world would have to wait for another hundred years until Reuben Ottenberg used blood typing to conduct transfusions and established the universality of type O blood.


What is Hematology? Hematologist in Hyderabad

There have been many inventions in the field of medicine, and even then, the concept of blood-related disorders is uncommon. There are many disorders that are related to blood but we are usually not able to judge whether the issue is in the organs or the blood. We do not know which doctor to consult when faced with certain symptoms.

Blood makes up a large portion of the human body. It has long been recognized as essential for surviving and as a component of the life force itself. It is a body fluid that contains components like red blood cells (commonly better understood as Hemoglobin), white blood cells (Leucocytes), plasma, and platelets. Blood runs through veins, arteries, and capillaries with a mixture of 55% plasma and 45% blood cells. Blood cells are formed in the stem cells of bone marrow. (A bone marrow is a spongy tissue inside your hip and thigh bones.) 

The role of blood in the human body involves the transfer of vital resources throughout the body, such as oxygen and nutrients. The stem cells which normally reside in bone marrow develop or create or produce red blood cells that help in carrying oxygen through the body; white blood cells which help in fighting infections; and platelets which help in bleeding control. The circulation of blood in the body also helps in regulating water flow and acidity in the body. 

Blood disorders may affect many of the body’s functions, such as the lymphatic system, a network of waste-clearing tissues, and organs. Heart diseases often arise from bone marrow complications. Hematology is aimed at explaining how these complications occur, how they affect the safety of an individual, and how they can be treated. 


Hematology can be defined as the study of blood and its components, the study of bone marrow a source of blood components, the study of lymph nodes a training center for blood components, and also the study of the spleen which function like graveyard storage of blood components. It covers the diagnosis, treatment, prevention of all these 4 organs disorders which can be cancerous/malignant like different forms of leukemia, lymphoma, and multiple myeloma,  or non-cancerous like anemia, sickle-cell anemia, thalassemia, aplastic anemia, pancytopenia, ITP, TTP, AIHA, Bleeding disorders (hemophilia), clotting disorders (DVT, Young stroke) etcetera. 

Diseases & Symptoms

If a person encounters any of the following symptoms then it’s time to visit a hematologist. Symptoms include weakness, giddiness,  shortness of breath, easy bruising, excess sweating, persistent back pain, recurrent infections, persistent fever, unintentional weight loss, nodular swelling neck, armpit, groin area, unexplained bleeding or clotting, unexplained high/low hemoglobin, unexplained high/low white blood cells and unexplained high/low platelets. Even if a patient is requiring or received any blood, platelets, or plasma transfusion then also he should visit a hematologist/ Hemato Oncologist to identify the root cause at an early stage. These symptoms could be the indicators of disease like anemia, sickle cell disease, thalassemia, malaria, bleeding disorders, blood cancer, thrombosis, and hypercoagulability. One should visit a hematologist if the mentioned symptoms persist.

Who is a Hematologist?

A hematologist is a person who treats these diseases. They operate in blood centers, anatomy labs, and private clinics. There are many specialists in this field of medicine. Specialists in this field of medicine concentrate their practice on either one of the areas of hematology.

A hematologist might have one of the following specialties:


  • Hemoglobinopathy – specializes in the study of lack of hemoglobin in the blood which can cause sickle cell disease, thalassemia, or other conditions.
  • Hematological Malignancy – focuses on the detection and management of blood cancers.
  • Anemias: studies the deficiency of hemoglobin or red blood cells.
  • Coagulopathy: studies bleeding disorder; this represents the capacity of the body to create blood clots.


Hematologists are qualified to handle blood and blood-related organs such as lymph nodes, spleen, thymus, and lymphoid tissues. Suppose any symptoms related to blood diseases are experienced; a hematologist would ask you to take some tests such as full blood count test, white blood cell test, platelets, clotting screens, blood enzyme test, bone marrow biopsy, blood transfusions, and mono screening.

Many blood disorders are life-threatening, which is why hematologists work so hard at their job. Long gone were the days when we used to fear not having a proper cure for certain diseases. At Hematology and BMT Institute International, we specialize in all kinds of blood tests and treatments of blood disorders and make sure that you receive the best treatment with personalized care and comfort with friendly doctors at less expense.

Are you considering visiting a hematologist? Dr. S.K Gupta, Gold medalist,  DM – Clinical Hematology and BMT (AIIMS, Delhi) at Hematology and BMT Institute International specializes in hemato-oncology and Bone Marrow Transplantation procedures.

To know more visit our website https://hematologybmt.com/ or contact us: +91 7780297660 or +91 9390447254.


patient testimonial


Hematology and BMT Institute International is a Hospital that specialises in the treatment of all forms of blood, bone marrow, lymph nodes, spleen disorders, cancer and non cancer disorders providing a wide variety of programs spanning from inpatient day care clinics, a blood bank and laboratory to an outpatient facility. HBII has successfully treated many patients, and Mir Mohammed Shoaib Ali is one of them. This is his story.

A child and his journey towards recovery

Mir Mohammed Shoaib Ali was diagnosed with cancer at a very young age in October 2019. It all started with a mild cough, cold and fever. Even after taking a lot of antibiotics and iron supplements, there was no difference in his health condition. After several CBC tests, it was revealed that the child had blood cancer. Both the parents were shattered but, despite the setback, they mustered the courage to assess the situation further in terms of the treatment, the procedure, and the risks factors behind it. Even after visiting a lot of doctors, they were not satisfied with the suggested course of treatment. It was after some research that they finally came to know about Hematology and BMT Institute International and met Dr S. K. Gupta. 

Dr. Gupta sat them down patiently and explained to them the treatment in detail; its phases, the procedures, medications, the possible outcomes of chemotherapy and its side effects. He explained to them that the treatment duration would be difficult for the family, and stressed on the measures they could take to overcome the difficult time. 

Firstly, the doctor recommended doing all the blood tests like CBC, LFT, RFT, CUE, blood and urine cultures, CRP, Serology and immunology test, PT, INR, and aPTT.  He then started giving the child antibiotics through IV-fluids to overcome the growth of the disease. The doctor cleared the bacterial infection from the blood and on 14th October advised the patient and his family to go for chemo-port installation procedure along with CSF/body fluid analysis for hematopoietic malignancy.

During the first phase of treatment, the doctor scheduled the Induction therapy where the child was kept on VCR, DOXO and IT-MTX in his protocol with intensive care and treatment for two months. In this time, the patient’s blasts disappeared (from 72% to 0%), haemoglobin level increased, and most importantly, TLC counts increased to 9.611 from 1.6/ml. 

All the necessary precautions and measures were taken to make sure that the boy would have the strength to overcome cancer. He conducted regular checkups, blood tests and also charted out a diet plan which was rich in proteins, so that the kid would have the strength during chemotherapy sessions.  Even during the COVID-19 pandemic, Dr Gupta successfully treated the child without causing any sort of complications. 

There was a huge difference in the boy’s health after he started receiving treatment from Dr S K Gupta. The ecstatic mother said,  

I would recommend Dr S K Gupta sir, who is highly experienced, thoroughly professional and an expert in treating blood-related disorders. I must say he is one of the top hematologists in the world.” 

Dr S.K.Gupta is highly experienced in treating blood related disorders. He specialises in treating blood, bone marrow, lymph nodes and spleen disorders. He is very compassionate towards his patients and their families. He listens to all queries patiently, and provides knowledge in the most simpler terms. He is one of the renowned hematologists in India who practices at the Hematology and BMT Institute International (HBII) in Hyderabad. 

HBII is one of the leading hematology and bone marrow transplant hospitals that offers all treatments related to blood disorders. The hemato-oncologists at HBII are well-versed in stem cell transplantation as well. Nurses and support staff are qualified to work with people of all ages suffering from blood disorders. HBII  provides world-class hemato-oncology treatment with a high success rate. The hospital is equipped with state-of-the-art equipment and manned by the trained and dedicated staff. 

If you or anyone in your social circle suffer from any symptoms that indicate blood-related disorders, then contact us. Call +91 77802 97660 or visit the website to know more: https://hematologybmt.com/


Peidatrics | Children’s BMT in Hyderabad

What is a Pediatric | Children’s Hematologist/Oncologist?

If your child or teens are facing some kind of blood disease or cancer, our Hematology and BMT Doctors are fully experienced pediatric hematologists/oncologists who have the experience and qualifications to evaluate and treat your child or teen. The Best care of children or teens with blood diseases and cancer is learned from advanced training and experience in practice. Pediatric hematologists/oncologists treat children and teens from birth through young adulthood.

Children and teens are not just small adults. Their bodies are growing and have unique medical needs. They usually express their concerns differently than adults do. They cannot always answer medical questions and are not always able to be patient and cooperative.

Pediatric hematologists/oncologists know how to examine and treat young children and teens in a way that makes them relaxed and cooperative. Most pediatric hematologists/oncologists’ offices are arranged and decorated with children and teens in mind.

Ours internationally recognized pediatric hematologists/oncologists and hematopathologists are diagnosing and treating all types of pediatric blood cancers.

To find the best pediatrician or Pediatrics Bone Marrow Transplant in Hyderabad click here.

Symptoms of Leukemia

What are the Symptoms and Signs of Leukemia?

Many types of leukemia produce no obvious symptoms within the early stages. Eventually, symptoms may include any of the following:

  • Anemia and related symptoms, like fatigue, pallor, and a general feeling of illness.
  • A tendency to bruise or bleed simply, as well as harm from the gums or nose, or blood within the stool or urine.
  • Susceptibility to infections like a sore throat or bronchial pneumonia, which can be in the midst of a headache, inferior fever, mouth sores, or skin rash.
  • Swollen humor nodes, generally within the throat, armpits, or groin.
  • Loss of appetite and weight.
  • Discomfort below the left lower ribs (caused by a swollen spleen).
  • Very high white blood corpuscle counts might lead to visual issues because of retinal hemorrhage, the ringing of the ears (tinnitus), mental standing changes, prolonged erection (priapism), and stroke.

Call Your Doctor regarding leukemia If:

Leukemia symptoms are often vague and not specific. You may overlook early leukemia symptoms because they may resemble symptoms of the flu and other common illnesses.

Rarely, leukemia may be discovered during blood tests for some other condition.

Book an Appointment with your doctor if you have any persistent signs or symptoms that worry you.

Request an Appointment at Hematology and BMT

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